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The standard NHS protocol for B12 deficiency typically involves hydroxocobalamin 1mg intramuscularly three times a week for two weeks (if there's no neurological involvement) or on alternate days until no further improvement (if neurological symptoms are present)

Apply gentle pressure with a clean cotton ball if needed

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Skin aging (reduced collagen, wrinkles): Fibroblasts lose repair capacity, leading to extracellular matrix degradation